In solid tumors significantly high levels of chromosome abnormalities have been detected, but distinction between significant and irrelevant events has been a major challenge. Consequently, the application of cytogenetic technology as diagnostic, prognostic, or therapeutic tools for these malignancies has remained largely underappreciated. The emergence of FISH is particularly useful for solid malignancies, and the spectrum of their application is rapidly expanding to improve efficiency and sensitivity in cancer diagnosis, prognosis, and therapy selection, alone or with other diagnostic methods.
[Back to top]
In solid tumors significantly high levels of chromosome abnormalities have been detected, but distinction between significant and irrelevant events has been a major challenge. Consequently, the application of cytogenetic technology as diagnostic, prognostic, or therapeutic tools for these malignancies has remained largely underappreciated. The emergence of FISH is particularly useful for solid malignancies, and the spectrum of their application is rapidly expanding to improve efficiency and sensitivity in cancer diagnosis, prognosis, and therapy selection, alone or with other diagnostic methods.
[Back to top]