Most information generated to date in the array CGH field has been generated using BAC CGH arrays. Kreatech has embraced this by launching products specifically meant for use with BAC arrays.
- The ULS array CGH labeling kits produce fluorescently labeled DNA within minutes. It is a robust, non-enzymatic method to detect gains and losses of chromosomal material including single copy number changes on BAC arrays
- The Genome-pULSe array CGH Genomic DNA Amplification and Labeling Kit offers a procedure that allows the uniform amplification and subsequent (non-enzymatic) labeling of whole genome from small samples. This method has been designed to provide a quick and highly reproducible amplification and labeling procedure for array CGH analysis on BAC arrays
Chromosome Plot
Left: SKBR3-female, phi29-amplified DNA (automated hybridization, by Simon Joosse, Dutch Cancer Institute, Amsterdam, The Netherlands).
Hybridization Image Scans
Hybridization image scans of male-female (left image), and a SKBR3-female (right image) BAC microarray hybridizations.
Most information generated to date in the array CGH field has been generated using BAC CGH arrays. Kreatech has embraced this by launching products specifically meant for use with BAC arrays.
- The ULS array CGH labeling kits produce fluorescently labeled DNA within minutes. It is a robust, non-enzymatic method to detect gains and losses of chromosomal material including single copy number changes on BAC arrays
- The Genome-pULSe array CGH Genomic DNA Amplification and Labeling Kit offers a procedure that allows the uniform amplification and subsequent (non-enzymatic) labeling of whole genome from small samples. This method has been designed to provide a quick and highly reproducible amplification and labeling procedure for array CGH analysis on BAC arrays
Chromosome Plot
Left: SKBR3-female, phi29-amplified DNA (automated hybridization, by Simon Joosse, Dutch Cancer Institute, Amsterdam, The Netherlands).
Hybridization Image Scans
Hybridization image scans of male-female (left image), and a SKBR3-female (right image) BAC microarray hybridizations.